“What is remarkable about Life Support is how it avoids every pitfall of the standard issue-based TV film and, indeed, of most TV films, period… Though the film is ‘inspired by a true story’ — Queen Latifah plays a role based on the sister of director and co-writer Nelson George, an HIV-positive former drug addict and current AIDS activist — it’s not, in the usual biopictorial sense, a true story… It’s about mothers and daughters, or the work that marriage takes, or loyalty to friends even when they mess up, or the righteousness and self-righteousness of a reformed drug addict.”
—Robert Lloyd, Los Angeles Times